Leptin and the leptin receptors. Leptin is carried by the bloodstream into your brain where it sends a signal to the hypothalamus — the part that controls when how much you eat.Leptin is a hormone that plays an important role in weight regulation. FOS- like antigen 2 ( FOSL2) is a key transcription factor that controls leptin expression in adipocytes [ ]. Leptin is a small protein hormone involved in the control of energy intake appetite metabolism. Leptin expression is regulated by a variety of hormones including insulin, glucocorticoids leptin itself [ ]. They travel through the blood stream into the brain specifically the hypothalamus where they stimulate neural receptors to. Leptin Obesity protein seems to play a role in regulating energy intake expenditure. This article reviews what leptin is how it works if supplements can help you lose weight.
It is 167 amino acid protein that has a amino terminal signal that is around 41 amino acids long. Leptin is a 16Kda protein coded by the obesity gene.